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Scientific Evidence on 12-Week Glutathione Use Study 1: Weschawalit et al., 2017 (Clinical, Cosmetic and Investigational Dermatology) Design: Double-blind, placebo-controlled study Duration: 12 weeks Result: Oral glutathione (250 mg twice daily) significantly reduced melanin index, brightened skin , and improved elasticity after 12 weeks compared to placebo