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In terms of antioxidant defense, it not only directly scavenges free radicals (Singh et al., 2011) but also activates the Nrf2/ARE axis (Ashrafizadeh et al., 2020), driving the expression of key enzymes such as glutathione S-transferase and catalase to systemically alleviate ROS accumulation
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Several medical reports, regulatory advisories, and reviews have documented severe, potentially life-threatening reactions tied to injectable glutathione especially when done in unregulated settings or with contaminated/inappropriately compounded products
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