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The dense capsule surrounding the enlarging prostate prevents it from further expansion outward, which in turn forces the prostate to press against the urethra, and partially block urine flow (Figure 2)

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Sheehan D, Meade G, Foley V, Dowd C (2001) Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily