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Specifically, pro-BDNF binds to the neurotrophin receptor p75NTR, triggering apoptotic signalling and neuronal pruning 1,7 , while mBDNF selectively binds to tropomyosin kinase B (TrkB) receptor, promoting neuronal survival and growth 4,9

After that initial period, it is common to continue injections monthly, though less frequent intervals might be OK if cobalamin blood levels are supportive

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As with all investigational therapies, full disclosure of your medical history to your provider is essential before starting any Cerebrolysin protocol