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Glycemic control in people with long-standing type 2 diabetes on basal insulin therapy has been challenging due to insulin titration inertia, but many also need additional therapy, said Julio Rosenstock, MD, Clinical Professor of Medicine at Texas Southwestern Medical Center

Obesity alone increases the risk for issues like diabetes, heart disease, and fatty liver

For example, the presence of a significant level of a hormone circulating in the bloodstream can cause its target cells to decrease their number of receptors for that hormone