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We additionally examined circulating DPP4 levels and the mRNA abundances of sheddases in a mouse model of severe metabolic liver disease without obesity, phosphatidylethanolamine N -methyltransferase ( Pemt / ) mice

We also include nutritional counseling, exercise recommendations, and weight loss drugs, including semaglutide and tirzepatide

Discussion and future direction Accumulating preclinical and early clinical work suggests that drugs targeting gut-brain peptide signaling are promising therapeutics for the treatment of AUD

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