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Common side effects that you may experience when taking Januvia or Janumet include: Upper respiratory infection Stuffy or runny nose and sore throat Headache Nausea, vomiting, diarrhea Upset stomach and indigestion (dyspepsia) Swelling of the hands or legs Low blood sugar (hypoglycemia) in people who take Janumet along with certain other medicine for diabetes

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Patients should be informed that biotin supplementation can interfere with certain laboratory tests, including thyroid function and cardiac troponin assays, as noted in FDA safety communications

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease