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This process is driven by the inactivation of glutathione peroxidase 4 (GPX4) and the pathological accumulation of lipid hydroperoxides (LPOs) within cellular membranes (Stockwell et al., 2017

doi: 10.3390/ijms25021322 113 YangBYangCLiuRSuiWZhuQJinYet al

Since 1 June 2025 that authorisation should follow a face-to-face assessment

Cruciferous vegetables are dual-acting: They provide some dietary glutathione directly AND activate Nrf2-mediated upregulation of glutathione synthesis genes via sulforaphane [27][28]