For a long time, MEL was considered as hormone occurring only in vertebrates, however, it turned out that MEL is a compound common in nature
"What's dangerous is that these people, presumably younger people, don't know what dose they're taking." The risk is compounded by the fact that diphenhydramine is frequently sold in formulations where it is combined with other over-the-counter drugs, such as acetaminophen (Tylenol), a medication that can cause liver failure when taken in large amounts
However, the use of such agents, often termed performance-enhancing drugs (PEDs), raises complex ethical, legal, and health-related considerations, necessitating a thorough understanding of their mechanisms of action, risks, and benefits
Sigma-Aldrich, Munich, Germany)