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These conditions digestive conditions, such as Crohns disease and ulcerative colitis autoimmune conditions, such as celiac disease and type 1 diabetes genetic conditions, such as inherited intrinsic factor deficiency and inherited transcobalamin deficiency chronic pancreatic disease pernicious anemia vitiligo Other factors that may lead to a vitamin B12 deficiency can include drinking excessive amounts of alcohol or using certain drugs, such as some heartburn medicines and metformin

On the other hand, conventional IVF or IVF-ICSI (intracytoplasmic sperm injection) would be the appropriate treatments when sperm quality is diminished by presenting a more severe form of varicocele, regardless if there are additional female infertility issues or not

To in vitro tests, human venous blood was collected from healthy volunteers that signed the Informed Consent Form (ICF)

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