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The principal mechanism of protraction resulting in the long half-life of semaglutide is albumin binding, which results in decreased renal clearance and protection from metabolic degradation

For someone who has difficulty getting enough B12 due to underlying health conditions or diet, this helps offset the need for smaller daily increments of B12 from diet or oral vitamins

The blood sugar effect of peptides is typically not a concern for non-diabetics, but in this case, the individual experienced severe gastrointestinal effects, highlighting the importance of caution when using these drugs 1m6s

Scientific References Vitamin B12 deficiency in over 16s: diagnosis and management