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Patients should be counseled that these symptoms are expected and generally not indicative of serious pathology, though persistent or severe symptoms warrant medical evaluation

Unlike injectable GLP-1s, Rybelsus delivers the active peptide through the mouth using an absorption-enhancing tablet technology, making it a unique option within the GLP-1 drug class

doi: 10.1056/NEJMra0910061 80 YangXLiuXNieYZhanFZhuB

In 3Tg-AD treated with DA-JC4, the ability of recognize new object and spatial working memory was improved, hippocampal A and tau pathology were alleviated, and hippocampal synaptic plasticity also was improved as well as levels of PSD95 and SYP were increased (235)