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Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway

Mitochondrial function naturally declines with age, and it is directly linked to reduced energy, slower metabolism, and increased susceptibility to age-related diseases

The copper delivery function may influence copper-dependent enzymes including lysyl oxidase (collagen crosslinking), superoxide dismutase, and cytochrome c oxidase