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It also incorporated a substantial body of observational evidence, making it the largest meta-analysis to date examining the relationship between GLP-1RAs and lower-extremity outcomes in this population

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Long-term efficacy and safety of 1 proteinase inhibitor treatment for emphysema caused by severe 1 antitrypsin deficiency: an open-label extension trial (RAPID-OLE)

Finally, ELISA analysis showed that L-carnosine markedly decreased the secretion of the pro-inflammatory cytokines IL-6 and TNF- following LPS stimulation (Figures 6G, H), indicating an anti-inflammatory effect