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doi: 10.1016/j.jnutbio.2020.108524 115 XiongHChenZLinBXieBLiuXChenCet al

Mice null for Fbxo40 have increased levels of IRS1 and demonstrate enhanced body and muscle size during the growth phase associated with elevated IGF1 levels. Moreover, IGF-1 LR3 also helps with muscle repair via improving the proliferative capacity of muscle satellite cells (MSCs)

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