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A growing body of evidence has shown that metals (including heavy metals) are able to generate ROS, which subsequently can lead to lipid peroxidation, thereby causing damage to DNA, as well as the consumption and eventual depletion of a cells antioxidant defence mechanisms

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Neurochem Res 45 , 14611480 (2020)

Effect of glucagon-like peptide-1 receptor agonists on heart rate in non-diabetic individuals with overweight or obesity: a systematic review and pairwise and network meta-analysis of randomized controlled trials