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Epub 2011/01/13

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At doses six times greater than its efficacious dose (60 mg/kg, PO), 710GO did not cause changes in telemeterized NHPs to any of the measured cardiac parameters, including systolic blood pressure, diastolic blood pressure, heart rate, and corrected QT interval ( Future directions The melanocortin system is well established as a key regulator of metabolic processes, leading many pharmaceutical and biotech companies to target these receptors, particularly MC4R, for their anti-obesity potential

Most human data is from topical dermatological applications