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Nitric Oxide Synthesis and Function Vasodilators, such as acetylcholine, bradykinin, and adenosine do not exert their effects upon the vascular smooth muscle cells in the absence of the overlying endothelium

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We have also shown that ductal cells found within isolated primary human islets exhibit a similar transcriptional signature as PANC-1 cells, particularly a strong transcriptional signature associated with type I IFNs, which may contribute to the cytokine storm preceding disease onset (116, 149)