can semaglutide cause heart problems In patients with cardiometabolic #HFpEF, #semaglutide and #tirzepatide reduced the risk of hospitalization for failure or all-cause mortality vs sitagliptin, but tirzepatide offered no additional benefit over semaglutide. https://ja.ma/3JO2SQc Semaglutide Cuts Heart Risk Beyond

He noted that during the last two quarters the penetration of the drugs has decreased even though there is more manufacturing capacity to produce the medications

Side Effects and Safety Considerations While generally well-tolerated, Semaglutide may cause side effects such as nausea, vomiting, and diarrhea, particularly during the initial stages of treatment

It works primarily through GLP-1R activation, slowing gastric emptying and increasing insulin secretion when glucose is elevated

In a blood pressure substudy, tirzepatide was associated with lower 24-hour systolic blood pressure compared with placebo after 36 weeks of treatment