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No Rebound Hunger or Metabolic Adaptation Appetite suppressants that work through central mechanisms (GLP-1 agonists, sympathomimetics, serotonergic agents) typically create tolerance over time, requiring dose escalation, and often produce rebound hunger when discontinued

Thirst can sometimes be mistaken for hunger

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31 coverage change, citing two key concerns echoed by hundreds of MOAA members and others whove shared their GLP-1 story: The move threatens the significant strides made by many GLP-1 users in reducing or eliminating weight-related ailments such as sleep apnea or high blood pressure while improving their quality of life