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those with less subcutaneous fat may use a 45-degree angle Never inject into areas that are tender, bruised, red, or hard Dose escalation and timing: Ozempic is typically initiated at 0.25 mg weekly for 4 weeks, then increased to 0.5 mg weekly, with further increases to 1 mg and potentially 2 mg weekly if needed for glycemic control Wegovy follows a 16-week escalation schedule: 0.25 mg 0.5 mg 1 mg 1.7 mg 2.4 mg, typically increasing every 4 weeks Administer once weekly on the same day each week