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BPC-157 operates primarily at the local tissue level: it upregulates VEGF and EGF expression at the injury site, modulates the nitric oxide system to improve blood flow to damaged tissue, and directly promotes fibroblast migration and collagen organization through the FAK-paxillin pathway

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In summary, after consideration of the public comment we received, we are finalizing with modification a New Technology APC assignment for HCPCS code C9789 to APC 1551 (New TechnologyLevel 14 ($1201-$1300)) with a payment rate of $1,250.50