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Respecto a la cianocobalamina (vitamina B12), su administracin puede ocultar sntomas de policitemia vera y agravar ciertas neuropatas como ambliopata tabquica o atrofia hereditaria del nervio ptico

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A 2024 case series in Journal of Clinical Endocrinology reported that patients receiving combination therapy showed 18% greater fat mass reduction compared to GLP-1 monotherapy, with improved energy scores on validated fatigue assessments (Morrison et al., 2024)