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Drug Treatment In this study, we used FOXO4 D-Retro-Inverso peptide (FOXO4-DRI, NovoPro, Shanghai, China) and ABT-263 (Apexbio Technology, Houston, TX, United States) to selectively remove the senescent chondrocytes

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This dual GIP/GLP-1 therapy effectively targets two key hormones to better regulate appetite and boost metabolism compared to single-hormone medications

Experts worry the drugs are being used as a tool to restrict eating or control weight in ways that can make eating disorders worse