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Before initiating treatment with Tirzepatide, a glucagon-like peptide-1 (GLP-1) receptor agonist , healthcare providers should check patients for a history of hypoglycemia (low blood sugar), especially if they are on concurrent treatments known to lower glucose levels like sulfonylureas or insulin

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The secondary outcomes were insulin, HOMA-IR, HbA1c, GLP-1, Glucagon, total cholesterol, triglycerides, HDL-C, low-density lipoprotein-cholesterol (LDL-C), ALP, AST, ALT, GT, TNF- , IL-6, hsCRP, antioxidant capacity and serum lipid peroxidation, body weight, body mass index (BMI), muscle mass, fat mass, and systolic and diastolic blood pressure Statistical analysis Sample size was established using the SigmaStat32 software, with significance level of 5% and 80% power

It could not comment on individual cases without proper investigation