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The researchers believe that an increase in acute mental stress triggered the double transitions of graying because pigmentation returned when the stress subsided

Superoxide dismutase catalyzes the dismutation reaction of superoxide to hydrogen peroxide, which is further catalyzed to the highly reactive hydroxyl radical and ultimately to water by glutathione peroxidase and catalase enzymes

While this is a helpful short-term survival mechanism, it becomes highly detrimental when the stress is chronic

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