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8 Remaining Questions and Knowledge Gaps There is strong evidence that synovitis drives worse outcomes in osteoarthritis, contributing to more severe and persistent pain, heightened pain sensitization, faster structural deterioration, and an increased need for joint replacement

Glutathione helps with getting rid of fat-soluble heavy metals and aids in the absorption of nutrients and minerals that also support detoxification

These improvements appear on standard metabolic panels and reflect the medication's core mechanismslowing stomach emptying to prevent rapid glucose spikes after meals

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