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Dose may be too low

In contrast, SGLT2i have metabolic effects on the myocardial and renal cells that mimic energy starvation, simulating autophagy and other changes that counteract the progression of HF

Now, an even more successful GLP-1, Mounjaro, is available in New Zealand, but at about $800 a month, Janet is tapping out of her experiment with GLP-1s

Following the identification of the cause, treatment can range from simple interventions, such as increasing fluid intake or adjusting the timing of medication, to more complex changes in therapy