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Strengths: No needles Patient compliance often significantly better than injection Portable and travel-friendly Generally well-tolerated Considerations: Bioavailability is lower than injection
Allow the skin to dry before proceeding
It missed its main target too, but a post hoc slice of the data, the patients taking fosgonimeton on its own without a standard Alzheimers drug alongside it, showed a striking signal on a brain-wave measure called P300 latency, a marker of processing speed, that moved 28 milliseconds in the right direction, along with a hint on a cognitive scale (ACT-AD topline, June 2022)
82 NiJ.QiuL.-J.ZhangM.WenP.-F.YeX.-R.LiangY.et al (2014)
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