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We encourage you to schedule an appointment if: Your period is delayed by more than 90 days (three months) You miss periods frequently or have irregular cycles You experience severe pain, abnormal bleeding, or other symptoms of hormonal imbalance While a mild delay in your period is often nothing to worry about, persistent or significant changes in your menstrual cycle should be evaluated

Obesity and the Regulation of Energy Balance. Cell Metabolism , 23(5), 777-787.