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Recent studies have also shown that RAGE and AGE-modified proteins are expressed in human ovarian tissue [35, 63]

10.1196/annals.1317.005 114

One of the most serious risks associated with Accutane treatment is the potential for severe birth defects if taken during pregnancy

These challenges have increased interest in herbal medicines and plant-derived compounds, many of which possess antioxidant, anti-inflammatory, and neuroprotective properties relevant to AMD pathogenesis [21, 22]