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Description

GLP-1 plays a central role in regulating appetite and digestion

Guidance on co-administration of commonly used drugs (Fig

Setmelanotide (Imcivree) has a different mechanism but is only approved for specific rare genetic obesity conditions, not general weight management

Future prospective studies with well-designed, larger independent, age matched cohorts including additional Saudi and regional MMA cohorts, detailed clinical phenotyping, renal function assessment, and standardized sample handling, are needed