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It belongs to a wider set of peptides moving through longevity and biohacker circles, including BPC-157, Cerebrolysin, Semax, Selank, Dihexa, P21, and the neurotrophic factors BDNF and klotho, whose human cognitive evidence ranges from thin to absent and which I reviewed in detail here

Unlike earlier broad-spectrum senolytics that can harm healthy tissue, FOXO4-DRI targets a molecular interaction unique to senescent cells

Dogan S, Aydin T, Koroglu N, Yilmazer Y, Albayrak N, Cetin F, Moshfeghi E, Celik O (2024) Assessing the efficacy of a novel sperm-washing medium enriched with serotonin, L-carnitine, and coenzyme Q10: an observational cohort study

Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (surpass-3 MRI): A substudy of the randomised, open-label, parallel-group, phase 3 surpass-3 trial