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DFP has been found to not only reduce the growth of some strains of common Gram-negative nosocomial pathogens, but also reduce the minimum inhibitory concentrations of antibiotics (Thompson et al., 2012)

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In murine models of breast cancer, ICIE significantly transformed the TME from immunologically cold to hot by diminishing immunosuppressive cells (Tregs, M2-TAMs, MDSCs), augmenting the infiltration of CTLs, and elevating the CD 8+ /Treg ratio