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#DDW2025 OBESITY AND IBD by @EdwardLoftus2 Obesity is a chronic inflammatory statue Adipose tissue is not biologically inert (TNFa, IL-6, IL-8, leptin, adiponectin) Postulated role in the pathogenesis of IBD Potential risk factor for adverse outcomes Trends in BMI among IBD patients at diagnosis in Olmsted County, Doubling of obesity rates in 20 years in CD and UC (Johnson AM JCC 2021 and J Clin Gastro 2024) Obese patients more likely to have a colonic phenotype
Amlodipine and valsartan tablets may be used to lower high blood pressure (hypertension) in adults Amlodipine and valsartan tablets have not been studied in children under 18 years of age
Breastfeeding mothers require 2.0 g daily, whilst children's needs range from 0.3 g in infancy to 1.5 g in adolescence
B12 shots at Precision Health & Training are generally very safe with minimal side effects
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