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One potential mechanism could be increased prevalence of NAION risk factors in patients starting GLP-1RA or that sudden and rapid decline in blood glucose could increase the risk of diabetic papillopathy or worsened DR

Some highlight retatrutides rapid weight loss benefits while dancing around the fact that the medication hasnt been FDA approved

"Scientists have had a hard time getting this drug into the body where it didn't get broken down in the GI tract by the stomach acid," Egan said

Orforglipron can help with weight loss by: Triggering receptors in your brain to reduce hunger and curb cravings (food noise) Slowing stomach emptying, which keeps you feeling fuller for longer Stimulating the production of insulin, which can help keep your blood glucose levels stable Like other GLP-1 medications, orforglipron needs to be combined with a healthy diet and exercise to achieve the best results