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These mechanisms have yet to be confirmed in humans [10]

NMDA and glycine regulate the affinity of the Mg2+-block site in NR1-1a/NR2A NMDA receptor channels expressed in Xenopus oocytes

Henson SM, Lanna A, Riddell NE, Franzese O, Macaulay R, Griffiths SJ, et al

3 COMT inhibitors, such as entacapone, opicapone, and tolcapone, and MAO-B inhibitors, such as selegiline, rasagiline, and safinamide, work by enhancing levodopas duration of action with inhibition of their respective enzymes