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Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia

This therefore increases the chances of misdiagnosis, delayed appropriate treatment, and poor clinical outcomes (De Sanctis et al

These results were confirmed in vivo , with an estimated lower plasmatic concentration of quercetin (nM) (similarly to other studies (7173)) during which quercetin reduced RV-RNA at 1 day post-infection, modulated KC, MIP-2, TNF-a, and MCP-2, decreased virus-induced airway hyper-responsiveness, and modulated IFNs (IFN- and IFN-2) (70)

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