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Several variables, including the improvement in bean quality, the growth of specialty coffee shops, and the spread of literature relating coffee use to health advantages, could explain the ongoing rise in coffee demand (Celli & Camargo, 2019)

Kaempferol exemplifies multi-targeted efficacy: by downregulating ERK, JNK, and p38 expression, it suppresses MAPK signaling to reduce MMP-2/9 activation, thereby inhibiting adhesion, migration, and invasion in breast cancer MDA-MB-231 cells