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Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis

The rate constant for the reaction between ascorbic acid and superoxide (at pH 7.4) using the xanthinexanthine oxidase system was estimated to be 5.4 10 6 M 1 s 1 (Som et al

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