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Mitochondrial glutamate generated via these catabolic pathways can be exported from mitochondria to the cytosol through the SLC25A18 and SLC25A22 transporters 21 , and cytosolic glutamate then participates in the biosynthesis of glutathionea tripeptide comprising glutamate, cysteine, and glycineand NEAAs (alanine, proline, aspartate, asparagine, and arginine) and is used as an exchange factor for importing extracellular cystine via SLC7A11

However, mounting evidence now suggests that VC is an active, highly regulated, and resembling the bone-forming process known as osteogenesis

This potent antioxidant helps the body remove harmful toxins and free radicals to keep the risk of cell damage at bay

Notably, brain aging and AD share common clinical and neuropathological features as well as similar etiologies and pathogenesis 20