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Among the regulators of bone metabolism, transforming growth factor TGF- is a multifunctional protein that can play a key role in cell proliferation, differentiation, apoptosis, and related tissue development through an autocrine/paracrine/endocrine approach ( In addition, TGF- has a typical transduction function in bone

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Therefore, microsphere sustained-release technology is being utilized to enable GLP-1 drugs to be released slowly and continuously, or GLP-1 molecules are being modified and optimized through structural modifications to develop GLP-1 RAs with longer half-lives

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