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Microfluidic based models also are designed to include the stress of the blood flow in BBB physiology but also closer replicate BBB structure with thicker membranes [117]

In addition to a subcutaneous formulation, Viking is also developing an oral version of VK2735, which elicited a 3.3% reduction in body weight versus placebo, according to a Phase I readout posted in March 2024

Used in metabolic and body composition studies

It is noteworthy that all enrolled children demonstrated relatively low BMI values at baseline, reflecting the high prevalence of protein-energy wasting and growth impairment among pediatric patients receiving maintenance hemodialysis