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222 Although limited direct evidence has evaluated use of GLP-1s with or without RDN-provided MNT, the SCALE, 13 STEP 1, 14 SURMOUNT, 15 and STEP 3 178 trials each demonstrated substantial weight reduction by combining GLP-1s with regular counseling sessions by RDNs or other qualified healthcare professionals (such lifestyle support was also provided to the placebo group in each trial)
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The mean [SD] Body Mass Index (BMI) was 26 [6], and comorbidities were present in 74.6% of patients
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