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The roller coaster ride to the first GLP-1 obesity drug While approved first as a drug for diabetes, very early on in its development, when Knudsen first began work on liraglutide she wondered if the same drug could also be used as a treatment of obesity (Molteni, Chen)
Both may be used in medical weight management when appropriate, but they differ in mechanism, dosing, tolerance, expected response, and patient suitability
Currently, no dietary supplement patch has been approved by the FDA for weight loss or to manage obesity
For the phase III clinical program, a total of eight studies were initiated that investigated the efficacy and safety of tirzepatide in comparison to various other established antidiabetic medications in T2D either in monotherapy, combination with metformin as baseline therapy, or metformin and insulin glargine as a baseline
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