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If fatigue is accompanied by persistent severe nausea, vomiting, or inability to maintain adequate oral intake, medical evaluation is essential to prevent complications such as dehydration, malnutrition, or acute kidney injury

For example, for every cup of coffee, drink an additional cup of water

Staying hydrated while taking a GLP-1 is often an overlooked part of the equation, even though proper hydration plays an important role in supporting your overall health during treatment

In summary, a PBPK model of tirzepatide in adults was developed and verified to mechanistically describe the in vivo process of tirzepatide after SC administration