oral vs injectable b12 Injections Supplements: Which are more effective? Vitamin B12 Injections vs. Oral

The reality we see consistently: researchers who combine AOD-9604 and 5-Amino-1MQ with structured fasted-state administration and exercise timing report reductions in subcutaneous adipose depots that single-agent protocols rarely match, even at higher doses

Data are lacking from long-term studies to assess whether oral treatment is effective when doses are administered less frequently than daily

PMID 24994676

While the NIH does not specify a tolerable upper intake level for vitamin B12, a study published in the JAMA Network Open found that high intakes of vitamin B12, such as from daily supplementation of 25 micrograms or higher, increased the risk of bone fracture [3] [4]