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And it was really helpful because Saxenda winded up not being available

Participants started on a daily dose of 500 mg, increasing gradually to 2,000 mg

Through increased labeling of BCKA-derived metabolites and increases in levels of BCAA breakdown, such as glutamate, alanine, and 3-hydroxyisobutyric acid, they discovered that tirzepatide treatment stimulated catabolism of BCAAs/BCKAs in BAT