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Through this journey, I also had the privilege of reconnecting and initiating collaboration with my PhD supervisor, Prof Maree Smith AC, and my former lab mate, Dr Andy Kuo, almost a decade later

Patients report fewer overlapping side effects, but appetite and cravings often return during the gap week

Experimental dermatologic and ulcer repair efforts have suggested tolerance and a capacity to support cutaneous regeneration

The in vivo arm of the study involved treatment of the HFD mice, including AMPK1/2 knockout mice, with 50-mg/kg/day metformin in the drinking water and then assaying hepatocytes in vitro with the results indicating that complex 1 activity, mitochondria density and mitochondrial DNA were all increased via an AMPK-dependent mechanism (138)