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Description

Alterations of these metabolites contribute to the regulation of hypoxic response, red blood cell sickling, inflammation, and clinical disease severity 11

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For decades, the quest for lighter skin has led to the rise of various skin-lightening products, many of which claim to reduce melanin production

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Methotrexate reduces tissue inflammation, slows down the destruction of tissue and cartilage, and has multipotent therapeutic effects on various immune cells and mediators (90, 91)

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